Physical and psychological dependence can occur within two weeks at a daily dosage of 300-600 mg, with overdose occurring at eight 300-mg tablets.Tolerance can develop after four days, requiring more and more of the drug to achieve the same results. At this point, overdose become a real possibility. Physical tolerance rises more slowly than psychological tolerance; while the abuser's head is calling for more ludes, his body is crying "Enough already!"
Dependence is indicated when withdrawal symptoms begin: headache, fatigue, dizziness, "pins and needles" in limbs, nausea, gastric problems, restlessness, anxiety, anorexia and dry mouth. As withdrawal continues in the heavy user, insomnia, cramps, tremors, seizures, vomiting, and depression are added to the symptoms, making it similar to "cold-turkey" withdrawal from heroin or barbiturates.
If you or someone you know is likely faced with an addiction to Methaqualone, please contact AToN Center's prescription drug treatment in San Diego.